Manchester United will be without Anthony Martial and Jesse Lingard for Monday's FA Cup clash at Chelsea with both sidelined for up to three weeks after picking up injuries during Tuesday's Champions League defeat by Paris Saint-Germain.
The in-form duo will also miss Liverpool's visit to Old Trafford in the Premier League on February 24 and face a race against time to make the second leg of the last 16 tie against PSG in the French capital on March 6.
"I think they'll be out for two-to three weeks," United caretaker manager Ole Gunnar Solskjaer said on Friday.
Martial sustained a groin problem in the early stages of Solskjaer's first defeat in charge, but was able to carry on until half-time before being substituted.
England international Lingard pulled up with a hamstring injury towards the end of the first half.